The great secret of succeeding in conversation is to admire little, to hear much; always to distrust our own reason, and sometimes that of our friends; never to pretend to wit, but to make that of others appear as much as possibly we can; to hearken to what is said and to answer to the purpose.
A little neglect may breed mischief ... for want of a nail, the shoe was lost; for want of a shoe the horse was lost; and for want of a horse the rider was lost.
Necessity never made a good bargain.
We must indeed all hang together, or, most assuredly, we shall all hang separately.
No nation was ever ruined by trade.
I should have no objection to go over the same life from its beginning to the end: requesting only the advantage authors have, of correcting in a second edition the faults of the first.
I have always thought that one man of tolerable abilities may work great changes, and accomplish great affairs among mankind, if he first forms a good plan, and, cutting off all amusements or other employments that would divert his attention, make the execution of that same plan his sole study and business.
Be studious in your profession, and you will be learned. Be industrious and frugal, and you will be rich. Be sober and temperate, and you will be healthy. Be in general virtuous, and you will be happy. At least you will, by such conduct, stand the best chance for such consequences.
We are more thoroughly an enlightened people, with respect to our political interests, than perhaps any other under heaven. Every man among us reads, and is so easy in his circumstances as to have leisure for conversations of improvement and for acquiring information.
Furnished as all Europe now is with Academies of Science, with nice instruments and the spirit of experiment, the progress of human knowledge will be rapid and discoveries made of which we have at present no conception. I begin to be almost sorry I was born so soon, since I cannot have the happiness of knowing what will be known a hundred years hence.